The physiology of dumping includes release of vasoactive substances from the small intestine into the blood stream in response to hyperosmolar foods such as sugars and starches and an inrush of fluid into the small bowel that dilutes the sugars and causes lowered blood pressure. Some of the vasoactive substances include serotonin, bradykinin, substance P, pancreatic polypeptide, insulin, glucagon, neurotensin, and enteroglucagon. This is a complex syndrome that is incompletely understood.
Learn more in our section on Iron Deficiency.